But chances of the agenda being hijacked by the alleged affair are high. A similar event staged by predecessor Nicolas Sarkozy after his 2007 divorce was dominated by curiosity over his ties to singer Carla Bruni, whom he subsequently wed.
While a poll at the weekend showed four-fifths of French voters considered the matter a private affair for Hollande and his family, the news of former journalist Trierweiler's admission to hospital prompted critics to break their silence.
Although France does not have an official First lady title, Trierweiler has her own office in the Elysee, a chauffeur and adviser, and accompanies Hollande on visits. Many pundits say it is legitimate now to question what her actual status is.
"She knows it must be cleared up because the debate has turned political," Frederic Gerschel, a reporter for the Le Parisien daily, told RTL radio after speaking to Trierweiler.
Her office said she would remain in hospital for the time being. "She needs to recover after the shock she suffered. She needs peace and quiet," an aide said.